Table 3

Clinical symptoms, seroconversion, and RT-PCR detection of NV in stool samples and hand rinse samples collected from 12 subjectsc

Subject statusSubject IDIllnessaSeroconversionbStool sample resultHand rinse sample result
RT-PCRRT-qPCRMax titer (log10/g)Total no.No. of Pos RT-qPCRsNo. of Pos HybMean log10 (no. of GEC/hand)
Infected34YesYesPosPos8.38223.94
36YesYesPosPos8.12212d183.74
37YesYesPosPos7.41201
40YesYesPosPos7.5900
46YesYesPosPos7.48223.30
54YesYesPosPos8.212224.45
7118253.86
Uninfected38NoNoNegNeg1600
41YesNoNegNeg900
42YesNoNegNeg17232.81
44NoNoNegNeg1600
47NoNoNegNeg1400
55NoNoNegNeg1600
88232.81
  • a Illness, ≥3 loose or watery stool samples and/or any vomiting within 24 h.

  • b ≥4-fold difference between the prechallenge and convalescent-phase serum NV-specific IgG titers.

  • c Pos, positive; Neg, negative; Hyb, hybridizations.

  • d At least one sample was confirmed positive by sequencing.