Table 5

GC-MS analysis of alkane oxidation by CYP63A2a

AlkaneNo. of carbon atomsAlkane oxidation (%)Oxidation metabolite (BSTFA derivative)
MWbIon fragmentscMetabolited
n-Nonane924.7216.4201, 171, 143, 115, 103, 83, 75, 55, 411-Nonanol
n-Decane1015.1230.4215, 171, 139, 115, 103, 83, 751-Decanol
n-Undecane1116.5244.4229, 143, 83, 75, 551-Undecanol
n-Dodecane1217.0258.5243, 215, 185, 155, 129, 103, 75, 431-Dodecanol
n-Pentadecane159.1300.6285, 257, 199, 159, 103, 75, 431-Pentadecanol
n-Hexadecane1619.8eNDf
n-Heptadecane1730.7328.6313, 238, 199, 167, 103, 75, 431-Heptadecanol
n-Octadecane1831.1ND
n-Nonadecane1919.9356.7341, 255, 213, 167, 103, 75, 431-Nonadecanol
  • a See Fig. S2 in the supplemental material for the GC-MS profiles of metabolites.

  • b MW, molecular weight.

  • c Numbers are m/z values.

  • d Identification of metabolites was performed using a standard NIST traceable MS database, with TMS-derivatized alcohols downloaded from NIST standard reference database number 69 (available at http://webbook.nist.gov/chemistry/).

  • e —, not applicable.

  • f ND, not detected.