TABLE 1

Amino acid alterations in BDNF mutants

Amino acid positionAmino acida in:
Wild typeDE Rd1DE Rd2
T4T5B2B5P1P3P5P10K3K6K8
11SerCysCysCysCysCysCysCys
34GlyGluGluGluGluGlu
40GluAspAspAsp
41LysGluGluGluGluGlu
48GlnArgArgArgArgArg
50LysAla
61MetThr
66GluGlyGlyGlyGlyGly
67GlyCysCys
73LysGlu
83ThrAla
95LysGlu
108SerAlaAlaAlaAlaAlaAlaAla
115IleSerSer
  • a —, same residue as in the wild type.