TABLE 1

Multiple comparisons of Cox mixed-effects survival modelsa

Microbiota comparedCox statistic for time to:
PupationEclosion
EstimatebSEz valueP valueEstimatebSEz valueP value
A. pomorum–axenic1.3270.05922.324<0.0011.1780.06019.634<0.001
A. tropicalis–axenic1.4760.05925.114<0.0011.5380.06025.595<0.001
5-Species–axenic1.2500.05921.324<0.0010.9740.05916.507<0.001
L. brevis–axenic0.3890.0576.797<0.0010.3340.0595.694<0.001
L. fructivorans–axenic−0.0070.057−0.11910.0130.0580.2251
L. plantarum–axenic0.3520.0586.105<0.0010.2660.0594.521<0.001
A. tropicalisA. pomorum0.1500.0592.5370.140.3600.0606.034<0.001
5-Species–A. pomorum−0.0770.059−1.3070.84−0.2040.060−3.4120.01
L. brevisA. pomorum−0.9370.059−15.826<0.001−0.8440.060−14.087<0.001
L. fructivoransA. pomorum−1.3340.059−22.493<0.001−1.1650.060−19.534<0.001
L. plantarumA. pomorum−0.9750.060−16.380<0.001−0.9120.060−15.175<0.001
5-Species–A. tropicalis−0.2270.058−3.8890.001−0.5640.060−9.466<0.001
L. brevisA. tropicalis−1.0870.058−18.608<0.001−1.2040.060−20.191<0.001
L. fructivoransA. tropicalis−1.4830.059−25.303<0.001−1.5250.060−25.538<0.001
L. plantarumA. tropicalis−1.1250.059−19.080<0.001−1.2720.060−21.216<0.001
L. brevis–5-species−0.8600.059−14.670<0.001−0.6400.059−10.784<0.001
L. fructivorans–5-species−1.2570.058−21.484<0.001−0.9610.059−16.358<0.001
L. plantarum–5-species−0.8980.059−15.254<0.001−0.7080.060−11.907<0.001
L. fructivoransL. brevis−0.3960.057−6.928<0.001−0.3210.058−5.497<0.001
L. plantarumL. brevis−0.0380.057−0.6560.99−0.0680.059−1.1590.90
L. plantarumL. fructivorans0.3580.0586.232<0.0010.2530.0594.316<0.001
  • a The Cox model makes a global comparison of development observations, using experimental replicate as a random effect. Pairwise comparisons of the Cox models were made by Tukey's HSD test implemented in the multcomp package for R, adjusting P values for multiple comparisons using the default (single-step) method.

  • b Restricted maximum likelihood estimate of the coefficient.