TABLE 1

Frequencies and abundances of the oMGs in the Borrelia afzelii-infected Ixodes ricinus nymphs are shown

ospC alleleospC statusaF1 (% [no.])bF2 (% [no.])cAbundancedMean abundancee
A9Native36.58 (25,108)67.32 (103)606,81185
A10Native37.93 (26,035)64.71 (99)545,915161
A2Native11.58 (7,950)32.03 (49)93,83931
A7Native3.51 (2,408)30.07 (46)145,29234
A14Native5.81 (3,988)20.91 (32)27,74622
A1Native4.41 (3,029)20.91 (32)199,09939
G13Exotic0.05 (33)13.07 (20)5,1957
G7Exotic0.04 (26)10.46 (16)177,2467
G2Exotic0.03 (19)10.46 (16)1502
G4Exotic0.02 (12)5.23 (8)9,1318
G15Exotic0.01 (10)4.58 (7)3355
G14Exotic0.01 (10)5.23 (8)2892
G6Exotic0.00 (3)1.31 (2)10815
TotalBoth100 (68,631)100 (153)1,811,156
TotalNative99.84 (68,518)100 (153)1,618,702
TotalExotic0.16 (113)35.95 (55)192,454
  • a ospC status refers to whether the oMGs are native to B. afzelii or were derived from B. garinii.

  • b Frequency 1 (F1) is the percentage of the oMG in the sample of sequences (n = 68,631 sequences). The number in parentheses represents the number of reads that belonged to that particular oMG.

  • c Frequency 2 (F2) is the percentage of the oMG in the sample of infected nymphs (n = 153 nymphs). The number in parentheses represents the number of nymphs that were infected with that particular oMG.

  • d Total spirochete load for each strain in all the ticks (n = 153 nymphs). This number is calculated as follows: multiply the estimate of the spirochete load (qPCR) by the strain-specific frequencies (454 sequencing) and then sum across all 153 nymphs.

  • e Geometric mean spirochete load per strain in the subsample of ticks infected with that strain (i.e., nymphs that were not infected with that strain were excluded from the calculation).