antivirulence

  • K2 Capsule Depolymerase Is Highly Stable, Is Refractory to Resistance, and Protects Larvae and Mice from <span class="named-content genus-species" id="named-content-1">Acinetobacter baumannii</span> Sepsis
    Public and Environmental Health Microbiology | Spotlight
    K2 Capsule Depolymerase Is Highly Stable, Is Refractory to Resistance, and Protects Larvae and Mice from Acinetobacter baumannii Sepsis

    Acinetobacter baumannii is an important nosocomial pathogen resistant to many, and sometimes all, antibiotics. The A. baumannii K2 capsular type has been associated with elevated antibiotic resistance. The capsular depolymerase characterized here fits the new trend of alternative antibacterial...

    Hugo Oliveira, Ana Mendes, Alexandra G. Fraga, Alice Ferreira, Andreia I. Pimenta, Dalila Mil-Homens, Arsénio M. Fialho, Jorge Pedrosa, Joana Azeredo
  • Amentoflavone Ameliorates <span class="named-content genus-species" id="named-content-1">Streptococcus suis</span>-Induced Infection <em>In Vitro</em> and <em>In Vivo</em>
    Public and Environmental Health Microbiology
    Amentoflavone Ameliorates Streptococcus suis-Induced Infection In Vitro and In Vivo

    The widespread use of antibiotics in therapy and in the prevention of Streptococcus suis infection in the swine industry raises concerns for the emergence of a resistant strain. The use of antivirulence agents has potential benefits, mainly because of the reduced selective pressure for the development of bacterial resistance. In this study, we found that amentoflavone...

    Xue Shen, Xiaodi Niu, Gen Li, Xuming Deng, Jianfeng Wang
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