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prebiotics

  • Synbiotic Matchmaking in <span class="named-content genus-species" id="named-content-1">Lactobacillus plantarum</span>: Substrate Screening and Gene-Trait Matching To Characterize Strain-Specific Carbohydrate Utilization
    Food Microbiology | Spotlight
    Synbiotic Matchmaking in Lactobacillus plantarum: Substrate Screening and Gene-Trait Matching To Characterize Strain-Specific Carbohydrate Utilization

    Synbiotics combine prebiotics and probiotics to synergistically enhance the health benefits associated with these ingredients. Lactobacillus plantarum is encountered as a natural inhabitant of the gastrointestinal tract, and specific strains are marketed as probiotics based on their strain-specific health-promoting activities. Strain-specific stimulation of growth...

    Jori Fuhren, Christiane Rösch, Maud ten Napel, Henk A. Schols, Michiel Kleerebezem
  • Prebiotics Inhibit Proteolysis by Gut Bacteria in a Host Diet-Dependent Manner: a Three-Stage Continuous <em>In Vitro</em> Gut Model Experiment
    Food Microbiology
    Prebiotics Inhibit Proteolysis by Gut Bacteria in a Host Diet-Dependent Manner: a Three-Stage Continuous In Vitro Gut Model Experiment

    Dietary protein levels are generally higher in Western populations than in the world average. We challenged three-stage continuous colonic model systems containing high protein levels and confirmed the production of potentially harmful metabolites from proteolysis, especially replicates of the transverse and distal colon. Fermentations of proteins with a prebiotic supplementation resulted in a change in the human gut microbiota and...

    Xuedan Wang, Glenn R. Gibson, Manuela Sailer, Stephan Theis, Robert A. Rastall
  • Prebiotic Supplementation of <em>In Vitro</em> Fecal Fermentations Inhibits Proteolysis by Gut Bacteria, and Host Diet Shapes Gut Bacterial Metabolism and Response to Intervention
    Food Microbiology
    Prebiotic Supplementation of In Vitro Fecal Fermentations Inhibits Proteolysis by Gut Bacteria, and Host Diet Shapes Gut Bacterial Metabolism and Response to Intervention

    Dietary protein intake is high in Western populations, which could result in potentially harmful metabolites in the gut from proteolysis. In an in vitro fermentation model, the addition of prebiotics reduced the negative consequences of high protein levels. Supplementation with a prebiotic resulted in a reduction of proteolytic metabolites in the model. A difference was seen in protein fermentation between omnivore and...

    Xuedan Wang, Glenn R. Gibson, Adele Costabile, Manuela Sailer, Stephan Theis, Robert A. Rastall
  • Two Novel α-<span class="sc">l</span>-Arabinofuranosidases from <em>Bifidobacterium longum</em> subsp. <em>longum</em> Belonging to Glycoside Hydrolase Family 43 Cooperatively Degrade Arabinan
    Enzymology and Protein Engineering
    Two Novel α-l-Arabinofuranosidases from Bifidobacterium longum subsp. longum Belonging to Glycoside Hydrolase Family 43 Cooperatively Degrade Arabinan

    We identified two novel α-l-arabinofuranosidases, BlArafC and BlArafB, from B. longum subsp. longum JCM 1217, both of which are predicted to be extracellular membrane-bound enzymes. The former specifically acts on α1,2/3-l-arabinofuranosyl linkages, while the latter acts on the α1,5-l-...

    Masahiro Komeno, Honoka Hayamizu, Kiyotaka Fujita, Hisashi Ashida
  • Food Microbiology
    Complementary Mechanisms for Degradation of Inulin-Type Fructans and Arabinoxylan Oligosaccharides among Bifidobacterial Strains Suggest Bacterial Cooperation
    Audrey Rivière, Marija Selak, Annelies Geirnaert, Pieter Van den Abbeele, Luc De Vuyst
  • Microbial Ecology
    An Attenuated Salmonella enterica Serovar Typhimurium Strain and Galacto-Oligosaccharides Accelerate Clearance of Salmonella Infections in Poultry through Modifications to the Gut Microbiome
    M. Andrea Azcarate-Peril, Natasha Butz, Maria Belen Cadenas, Matthew Koci, Anne Ballou, Mary Mendoza, Rizwana Ali, Hosni Hassan
  • Open Access
    Microbial Ecology
    Promising Prebiotic Candidate Established by Evaluation of Lactitol, Lactulose, Raffinose, and Oligofructose for Maintenance of a Lactobacillus-Dominated Vaginal Microbiota
    Stephanie L. Collins, Amy McMillan, Shannon Seney, Charlotte van der Veer, Remco Kort, Mark W. Sumarah, Gregor Reid
  • Food Microbiology | Spotlight
    A Human Gut Commensal Ferments Cranberry Carbohydrates To Produce Formate
    Ezgi Özcan, Jiadong Sun, David C. Rowley, David A. Sela
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