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Applied and Environmental Microbiology
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signal transduction

  • Nisin M: a Bioengineered Nisin A Variant That Retains Full Induction Capacity but Has Significantly Reduced Antimicrobial Activity
    Biotechnology | Spotlight
    Nisin M: a Bioengineered Nisin A Variant That Retains Full Induction Capacity but Has Significantly Reduced Antimicrobial Activity

    This study describes the generation of a nisin variant with superior characteristics for use in the NICE protein expression system. The variant, termed nisin M, retains an induction capacity comparable to that of wild-type nisin A but exhibits significantly reduced antimicrobial activity and can therefore be used at concentrations that are normally toxic to the expression host.

    Michelle O’ Connor, Des Field, Aoife Grainger, Paula M. O’ Connor, Lorraine Draper, R. Paul Ross, Colin Hill
  • Environmental Microbiology
    Oxidative Stressors Modify the Response of Streptococcus mutans to Its Competence Signal Peptides
    Matthew De Furio, Sang Joon Ahn, Robert A. Burne, Stephen J. Hagen
  • Physiology
    Regulation of Neurotoxin Production and Sporulation by a Putative agrBD Signaling System in Proteolytic Clostridium botulinum
    Clare M. Cooksley, Ian J. Davis, Klaus Winzer, Weng C. Chan, Michael W. Peck, Nigel P. Minton
  • Public Health Microbiology
    The Cyclic AMP (cAMP)-cAMP Receptor Protein Signaling System Mediates Resistance of Vibrio cholerae O1 Strains to Multiple Environmental Bacteriophages
    M. Shamim Hasan Zahid, T. M. Zaved Waise, M. Kamruzzaman, Amar N. Ghosh, G. Balakrish Nair, John J. Mekalanos, Shah M. Faruque
  • Genetics and Molecular Biology
    Identification of the Geobacter metallireducens BamVW Two-Component System, Involved in Transcriptional Regulation of Aromatic Degradation
    Javier F. Juárez, María Teresa Zamarro, María J. L. Barragán, Blas Blázquez, Matthias Boll, Kevin Kuntze, José Luis García, Eduardo Díaz, Manuel Carmona
  • Genetics and Molecular Biology
    Requirement of the Lactobacillus casei MaeKR Two-Component System for l-Malic Acid Utilization via a Malic Enzyme Pathway
    José María Landete, Luisa García-Haro, Amalia Blasco, Paloma Manzanares, Carmen Berbegal, Vicente Monedero, Manuel Zúñiga
  • Genetics and Molecular Biology
    Nitric Oxide as a Signaling Factor To Upregulate the Death-Specific Protein in a Marine Diatom, Skeletonema costatum, during Blockage of Electron Flow in Photosynthesis
    Chih-Ching Chung, Sheng-Ping L. Hwang, Jeng Chang
  • Evolutionary and Genomic Microbiology
    Genome of the Epsilonproteobacterial Chemolithoautotroph Sulfurimonas denitrificans
    Stefan M. Sievert, Kathleen M. Scott, Martin G. Klotz, Patrick S. G. Chain, Loren J. Hauser, James Hemp, Michael Hügler, Miriam Land, Alla Lapidus, Frank W. Larimer, Susan Lucas, Stephanie A. Malfatti, Folker Meyer, Ian T. Paulsen, Qinghu Ren, Jörg Simon, the USF Genomics Class
  • Genetics and Molecular Biology
    Directed Evolution of Vibrio fischeri LuxR for Improved Response to Butanoyl-Homoserine Lactone
    Andrew C. Hawkins, Frances H. Arnold, Rainer Stuermer, Bernhard Hauer, Jared R. Leadbetter
  • Genetics and Molecular Biology
    A Cyclic AMP Receptor Protein-Regulated Cell-Cell Communication System Mediates Expression of a FecA Homologue in Stenotrophomonas maltophilia
    Tzu-Pi Huang, Amy C. Lee Wong

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