signal transduction
- Biotechnology | SpotlightNisin M: a Bioengineered Nisin A Variant That Retains Full Induction Capacity but Has Significantly Reduced Antimicrobial Activity
This study describes the generation of a nisin variant with superior characteristics for use in the NICE protein expression system. The variant, termed nisin M, retains an induction capacity comparable to that of wild-type nisin A but exhibits significantly reduced antimicrobial activity and can therefore be used at concentrations that are normally toxic to the expression host.
- Environmental MicrobiologyOxidative Stressors Modify the Response of Streptococcus mutans to Its Competence Signal Peptides
- Genetics and Molecular BiologyRequirement of the Lactobacillus casei MaeKR Two-Component System for l-Malic Acid Utilization via a Malic Enzyme Pathway
- Evolutionary and Genomic MicrobiologyGenome of the Epsilonproteobacterial Chemolithoautotroph Sulfurimonas denitrificans
- Genetics and Molecular BiologyDirected Evolution of Vibrio fischeri LuxR for Improved Response to Butanoyl-Homoserine Lactone