Vibrio cholerae
Genetics and Molecular BiologyControl of Competence in Vibrio fischeriThe ability of bacteria to take up DNA (competence) and incorporate foreign DNA into their genomes (transformation) permits them to rapidly evolve and gain new traits and/or acquire antibiotic resistances. It also facilitates laboratory-based investigations into mechanisms of specific phenotypes, such as those involved in host colonization. Vibrio fischeri has long...
Physiologyl-Arabinose Induces the Formation of Viable Nonproliferating Spheroplasts in Vibrio choleraeVibrios spp. among other bacteria form transient cell wall-deficient forms as a response to different stresses and revert to proliferating rods when permissive conditions have been restored. Such cellular forms have been associated with antimicrobial tolerance, chronic infections, and environmental dispersion.
Genetics and Molecular BiologyMethionine Availability in the Arthropod Intestine Is Elucidated through Identification of Vibrio cholerae Methionine Acquisition SystemsMethionine is an essential amino acid involved in both biosynthetic and regulatory processes in the bacterial cell. To ensure an adequate supply of methionine, bacteria have evolved multiple systems to synthesize, import, and recover this amino acid. To explore the importance of methionine synthesis, transport, and recovery in any environment, all of these systems must be identified and mutagenized. Here, we have mutagenized every high-...
Genetics and Molecular BiologyCyclic di-GMP Increases Catalase Production and Hydrogen Peroxide Tolerance in Vibrio choleraeAs a result of infection with V. cholerae, patients become dehydrated, leading to death if not properly treated. The aquatic environment is the natural reservoir for V. cholerae, where it can survive alterations in temperature, salinity, and oxygen. The second messenger molecule c-di-GMP is an...
Environmental Microbiology | SpotlightNovel Cholera Toxin Variant and ToxT Regulon in Environmental Vibrio mimicus Isolates: Potential Resources for the Evolution of Vibrio cholerae Hybrid StrainsNatural diversification of CTXФ and ctxAB genes certainly influences disease severity and shifting patterns in major etiological agents of cholera, e.g., the overwhelming emergence of hybrid El Tor variants, replacing the prototype El Tor strains of V. cholerae. This report, showing the occurrence of CTXET comprising a novel variant of ctxAB...
Genetics and Molecular BiologyA Putative Acetylation System in Vibrio cholerae Modulates Virulence in Arthropod HostsThe bacterium Vibrio cholerae causes severe disease in humans, and strains can persist in the environment in association with a wide diversity of host species. By investigating the molecular mechanisms that underlie these interactions, we can better understand constraints affecting the ecology and evolution of this global pathogen. The...
- Evolutionary and Genomic MicrobiologyRedefinition and Unification of the SXT/R391 Family of Integrative and Conjugative Elements
- Methods | SpotlightQuantifying Vibrio cholerae Enterotoxicity in a Zebrafish Infection Model
- Public and Environmental Health MicrobiologyVibrio cholerae Colonization of Soft-Shelled Turtles